Coronavirus disease-2019 in a newborn: an autopsy and postmortem histology case report

The article presents the results of the pathological examination of the coronavirus disease in a child who lived 5 hours after the birth. The results. There was found at the autopsy examination focal meningoencephalitis (bacteriological examination - St. Aureus, St. Epidermidis), focal productive ependymitis, atelectasis of the left lung, bilateral polysegmental hemorrhagic-bacterial pneumonia (PCR of sectioned material of lung tissue for RNA virus SARS-CoV-2 positive, bacteriological examination of the tissue of the trachea, bronchi, lungs - St. Epidermidis, Enterobacter cloacae), necrotic erosive tracheitis, bronchitis, bronchiolitis, infectious-toxic shock, DIC-syndrome with hemorrhages in the lungs, kidneys, adrenal glands, serous membranes, total hemorrhage in the left adrenal gland with the formation of a cystic cavity, fetal hepatitis with multiple foci of extramedullary hematopoiesis, interstitial nephritis with necrosis of the epithelium of the renal tubules, erosive-necrotic esophagogastroenteritis (bacteriological examination - Enterobacter cloacae), edema of the brain, lungs, dysplasia of the thymus with depletion of peripheral immune organs, parietal deciduitis. The detected changes in internal organs and tissues led to the development of multiple organ failure, which became the direct cause of the death of the newborn child. Conclusion. The data of multisystem morphological changes caused by SARS-CoV-2 in a newborn child presented in the article allows to enrich the small number of reports on neonatal loss in the case of coronavirus disease-2019 and to increase the awareness of neonatologists and pathologists about the clinical and morphological features of the disease. Further research will help improve the diagnosis and treatment of coronavirus disease in children.