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Published January 5, 2023 | Version v1.0.0
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TRISTAN-rat

  • 1. Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, UK
  • 2. Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, UK

Description

First release of TRISTAN-rat repository to accompany the manuscript "Use of physiologically based pharmacokinetic and tracer kinetic models for prospective prediction and quantification of hepatic transporters drug-drug interaction via in vivo imaging in rats" by Nicola Melillo, Daniel Scotcher, J. Gerry Kenna, Claudia Green, Catherine D. G. Hines, Iina Laitinen, Paul D. Hockings, Kayode Ogungbenro, Ebony R. Gunwhy, Steven Sourbron, John C. Waterton, Gunnar Schuetz, and Aleksandra Galetin (referred to as the 'Six Test Compounds' study).

Accompanying datasets for these scripts may be found at Rat gadoxetate MRI signal dataset for the IMI-WP2-TRISTAN Six Test Compounds study | Zenodo.

Notes

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Files

QIB-Sheffield/TRISTAN-rat-v1.0.0.zip

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Additional details

Funding

IB4SD-TRISTAN – Imaging Biomarkers (IBs) for Safer Drugs: Validation of Translational Imaging Methods in Drug Safety Assessment - Sofia ref.: 116106 116106
European Commission