Published December 6, 2022
| Version version1
Dataset
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Neurometabolic changes in a rat pup model of type C HE - 1H MRS dataset (hippocampus)
Description
1H MRS in hippocampus was used to study longitudinally the effect of chronic liver disease (bile duct ligated rat model) in the brain (type C hepatic encephalopathy) of animals having developed disease a post natal day 15 (p15) corresponding to ~4 months old human brain. The dataset contains MR spectra and LCModel Quanifications from 7 bile duct ligated and 8 control animals at week 2, 4 and 6 after surgery.
Please cite the following manuscript if you are using these data
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MRS_data_LCModel.zip
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(45.8 MB)
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Additional details
Funding
- Enhanced MR Spectroscopic mapping of brain regional changes in type C hepatic encephalopathy of juvenile rats to develop novel combinatorial treatments 310030_201218
- Swiss National Science Foundation
- Translational Non-Invasive Metabolic Studies towards Novel Treatments of Chronic Hepatic Encephalopathy in Developing Brain, from 3D Organotypic Brain Cell Cultures to the In vivo Rat and Human Brain 310030_173222
- Swiss National Science Foundation