Published July 16, 2022 | Version PDF
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Physicochemical, Phytochemical Screening and Evaluation of Antidiabetic Activity of Ficus dalhousiae Fruits on Alloxan Induced Diabetic Rats

  • 1. Department of Pharmacognosy, Jagan's Institute of Pharmaceutical Sciences, Jangala Kandriga (V), Muthukur (M), SPSR Nellore-524 346, Andhra Pradesh, India
  • 2. Jagan's Institute of Pharmaceutical Sciences, Jangala Kandriga (V), Muthukur (M), SPSR Nellore-524 346, Andhra Pradesh, India

Description

The aim of the present study was to evaluate Physicochemical, Phytochemical Screening of Antidiabetic Activity of Ficus dalhousiae Fruits in Alloxan Induced Diabetic Rats. A plant material like “Ficus dalhousiae” member of the genus Moraceae, and physico chemical standards used for ash values. In statistical analysis, all data were represented in mean ± SEM (Standard error mean) values expressed as mean ± SEM of six samples data were analysed by one-way ANOVA followed by Dunnett's test. Effect of extracts of Ficus dalhousiae fruit on blood parameters against Alloxan induced Diabetic rats. The Physico-chemical standards of the fruit of Ficus dalhousiae have been carried out. The result shows that total Ash value was 6.7% w/w, water in soluble Ash 2.5% w/w and acid insoluble ash 0.7 w/w. Moisture content was 14.74% w/w. The water-soluble extractive values were 1.2%w/w, alcohol soluble extractive, Values 1.6% w/w and chloroform soluble extractive values were 4.6% w/v. Foaming index was 100., Fat content was 120mg, resin content was 250 mg, chloroform extract yield Was 4.3% w/w. In the present study alloxan administration induced a pronounced increase in the concentration of blood glucose and decreased glycogen in liver and muscles. A significant hyperglycaemia was attained with 24 hours after alloxan administration. The maximum effect was produced after 5 days.

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