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Published October 7, 2022 | Version v1
Poster Open

Representing Steerable Bases for cryo-EM in ASPIRE

  • 1. Princeton University
  • 2. KTH Royal Institute of Technology

Description

An introduction to the mathematical problem of cryo-electron microscopy (cryo-EM) is given, along with an overview of ASPIRE, an open-source Python package for processing cryo-EM image data. ASPIRE uses unique Fourier-Bessel basis representations for images of cryo-EM particles. The challenge of representing these mathematical structures within the ASPIRE codebase was addressed by building an extensible class hierarchy using mixins.

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