Hieracium waldsteinii (Asteraceae) and Onosma stellulata (Boraginaceae) as a Source of Antioxidant and Antimicrobial Agents
Creators
- 1. University of Belgrade, Faculty of Agriculture, Department of Chemistry and Biochemistry, 11080, Belgrade, Serbia.
- 2. University of Belgrade, Faculty of Agriculture, Department of Agrobotany, 11080, Belgrade, Serbia.
- 3. University of Belgrade, Institute for Biological Research 'Siniša Stanković', National Institute of Serbia, Department of Plant Physiology, 11060, Belgrade, Serbia.
- 4. Department of Experimental Oncology, Institute for Oncology and Radiology of Serbia, Pasterova 14, 11000, Belgrade, Serbia.
- 5. University of Belgrade, Institute for Biological Research 'Siniša Stanković', National Institute of Serbia, Department of Ecology, 11060, Belgrade, Serbia.
- 6. University of Belgrade, Faculty of Chemistry, Department of Analytical Chemistry, 11000, Belgrade, Serbia.
Description
The current study aimed to phytochemically characterize (including a detailed phenolic profile) two endemic Balkan's species (Hieracium waldsteinii and Onosma stellulata) and determine their possible application as a source of natural antioxidant and antimicrobial agents. The main phenolic compound in both species (in all examined parts) was chlorogenic acid. Eriodictyol, genistein and naringenin were quantified only in H. waldsteinii while isorhamnetin-3-O-rutinoside and sinapic acid were characteristic for O. stellulata. The highest antioxidant activity (98 mg AAE/g dry weight for TAC assay) was ascribed to the flower extract of H. waldsteinii while the lowest results (∼4.3 mg AAE/g dry weight for FRP assay) were exhibited by the extracts obtained from the plant's stem. Antimicrobial assays showed moderate antibacterial, i. e., moderate/strong activity against several tested fungi (in particular Trichoderma viride). Correlation analysis revealed strong positive connection between phenolic compounds and reducing power of extracts as well as between total phenolic and flavonoid content and the obtained minimal inhibitory concentration recorded in antibacterial assays.
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Additional details
Identifiers
- PMID
- 35213785
Related works
- Is part of
- 1612-1880 (ISSN)