LISINOPRIL AS IMMEDIATE RELEASE AND METOPROLOL AS SUSTAINED RELEASE BILAYERED TABLETS: FORMULATION AND EVALUATION

The development of a logical diagnostic strategy for drug estimate is the focus of this work. Pre-detailed consideration is given to readings of drug excipient similarity for excipient determination. making tablets using different polymers for drug delivery. to assess the pre- and post-pressure parameters of the detailed tablets. Analysis of the selected scheme's stability. Metoprolol, lisinopril, and the drug excipients blend were visible in the IR range. It was determined in the current analysis that there is no compound interaction between metoprolol, lisinopril, and the polymers used. It can be seen from the figure that there were no changes to these principal tops in the IR spectra of the mixture of drugs and polymers, suggesting that there were no physical interactions as a result of some bond creation between the drugs and polymers. This further supports the reliability of pure medication and the similarities between them and excipients.

Keywords: Lisinopril, Metoprolol, Bilayer Tablet, IR Spectra, Immediate release tablet.