Published May 9, 2019 | Version v1
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Rapid In Vitro Antifungal Property Assessment of Organic and Aqueous Extracts of Ganoderma lucidum Against Human Pathogenic Fungus of Aspergillus niger

  • 1. School of Studies in Biotechnology, PT. Ravishankar Shukla University, Raipur, India
  • 2. MATS University, Raipur, India

Description

   G. lucidum is commonly known as ‘Reishi.’ It has a variety of bioactive compounds. Aspergillus niger is common fungi, categorized with GRAS (generally recognized as safe) status by food and drug administration. However, due to its cosmopolitan nature, human beings get frequently exposed to spores and vegetative forms of A.niger. Mushroom has a wide diversity of bioactive components; the compound extraction process has an essential selection of suitable solvents for particular bioactive products for higher targetted efficiency activity. The present study took various organic and aqueous mediums for extract preparation. The rapid in vitro antifungal activity was analyzed. Among them, ethanolic extracts have shown potential, followed by other solvents in normal water, methanol, chloroform, and hot water. The current study result interpreted that owing to the new attraction to the properties of new antifungal products like fighting multidrug-resistant fungus. It is essential to develop a better understanding of the current methods available for screening and quantifying the antifungal effect of an extract or a pure compound for its applications in human health. 

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