Journal article Open Access

Enhancers display sequence flexibility constrained by transcription factor motif syntax

Reiter, Franziska; de Almeida, Bernardo P; Stark, Alexander

This repository holds the data necessary to reproduce all results and figures from the manuscript "Enhancers display sequence flexibility constrained by transcription factor motif syntax" for each of the main sections:

  • Random_variant_STARRseq
    • Random 8nt variants tested at seven enhancer positions in Drosophila S2 cells
  • Drosophila_motif_pasting_STARRseq
    • Systematic pasting of Drosophila TF motifs in hundreds of enhancer positions
  • Human_motif_pasting_STARRseq
    • Systematic pasting of human TF motifs in hundreds of enhancer positions

The code can be found at https://github.com/bernardo-de-almeida/Variant_STARRseq.

Files (635.9 MB)
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Drosophila_motif_pasting_STARRseq.zip
md5:1f44490875ab7d003acb18c95a7cff2a
136.6 MB Download
Human_motif_pasting_STARRseq.zip
md5:470b2d3f3038394f9e0dde4c51c59e82
186.7 MB Download
Random_variant_STARRseq.zip
md5:b109fd9ec7610a1b678198808946a600
312.6 MB Download
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