Published November 23, 2021
| Version 1.0
Dataset
Open
Data used in ECLIPSER methods paper and GTEx snRNA-seq cross-tissue reference map analysis
Authors/Creators
- 1. Massachusetts Eye and Ear, Harvard Medical School
- 2. Broad Institute of MIT and Harvard
Description
The tables were used in the papers: Rouhana*, Wang* et al., ECLIPSER: identifying causal cell types and genes for complex traits through single cell enrichment of e/sQTL-mapped genes in GWAS loci, bioRxiv 2021, doi: https://doi.org/10.1101/2021.11.24.469720; and Eraslan et al., Single-nucleus cross-tissue molecular reference maps to decipher disease gene function, bioRxiv 2021, doi: https://doi.org/10.1101/2021.07.19.452954. 'GTEx_v8_HG38_all_variants.tsv.gz' is an input file for running GWASvar2gene on GTEx v8 eQTLs and sQTLs, and all other files are input files for ECLIPSER.
Notes
This work was supported by the Chan Zuckerberg Initiative (CZI) Seed Network for the Human Cell Atlas awards CZF2019-002459 (A.V.S, J.M.R) and 2019-02455 (K.G.A.), National Institutes of Health, National Eye Institute R01 EY031424-01 (A.V.S, J.M.R, A.R.H., B.C.), and NIH, NHGRI 5U41HG009494 (S.A., F.A., K.G.A.), and funds from the Manton Foundation, Klarman Family Foundation and HHMI (A.R.).
Files
OpenTargetsGenetics_variant_and_gene_table_071620.csv
Files
(32.4 GB)
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