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Published March 18, 2021 | Version v1
Proposal Open

Protocol for a systematic review of the bactericidal activity of silver nanoparticles on drug-resistant bacteria.

  • 1. Universidad Autónoma de Ciudad Juárez

Contributors

  • 1. Universidad Autónoma de Ciudad Juárez

Description

(EN) As the field of nanomedicine grows, there is a greater need to understand the mechanisms of bactericidal action exerted by silver nanoparticles, considering the existence of more than one species of antibiotic-resistant bacteria. Given the above, the question arises: In what type of drug-resistant bacteria (Gram-positive or Gram-negative) are silver nanoparticles more effective as bactericides?

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(SP) A medida que el campo de la nanomedicina crece, existe mayor necesidad de comprender los mecanismos de acción bactericida que ejercen las nanopartículas de plata, considerando la existencia de más de una especie de bacterias resistentes a antibióticos. Dado lo anterior, se formula la interrogante: ¿En qué tipo de bacterias resistentes a fármacos (Gram positivas o Gram negativas) son más efectivas las nanopartículas de plata como bactericidas?

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References

  • [1] Y. N. Slavin, J. Asnis, U. O. Häfeli, and H. Bach, "Metal nanoparticles: Understanding the mechanisms behind antibacterial activity," J. Nanobiotechnology, vol. 15, no. 1, pp. 1–21, 2017, doi: 10.1186/s12951-017-0308-z.
  • [2] B. Felden and V. Cattoira, "Bacterial Adaptation to Antibiotics through Regulatory RNAs," Antimicrob. Agents Chemother., vol. 62, no. 5, pp. 1–11, 2018, doi: 10.1128/AAC.02503-17
  • [3] T. Baygar, N. Sarac, A. Ugur, and I. R. Karaca, "Antimicrobial characteristics and biocompatibility of the surgical sutures coated with biosynthesized silver nanoparticles," Bioorg. Chem., vol. 86, no. October 2018, pp. 254–258, 2019, doi: 10.1016/j.bioorg.2018.12.034
  • [4] B. Das et al., "Green synthesized silver nanoparticles destroy multidrug resistant bacteria via reactive oxygen species mediated membrane damage," Arab. J. Chem., vol. 10, no. 6, pp. 862–876, 2017, doi: 10.1016/j.arabjc.2015.08.008.
  • [5] F. A. El-Gohary et al., "Enhanced antibacterial activity of silver nanoparticles combined with hydrogen peroxide against multidrug-resistant pathogens isolated from dairy farms and beef slaughterhouses in egypt," Infect. Drug Resist., vol. 13, pp. 3485–3499, 2020, doi: 10.2147/IDR.S271261.
  • [6] C. H. N. Barros, S. Fulaz, D. Stanisic, and L. Tasic, "Biogenic nanosilver against multidrug-resistant bacteria (MDRB)," Antibiotics, vol. 7, no. 3, pp. 1–25, 2018, doi: 10.3390/antibiotics7030069.
  • [7] G. Franci et al., "Silver nanoparticles as potential antibacterial agents," Molecules, vol. 20, no. 5, pp. 8856–8874, 2015, doi: 10.3390/molecules20058856.