Source data for "Ca2+ channels couple spiking to mitochondrial metabolism in substantia nigra dopaminergic neurons"

Fig.1Aa-c.tif

2PLSM images (Fura-2 filled neuron) used for the reconstruction in Fig.1A

 

Fig1CDJ.xlsx

Numerical data for the charts in Fig. 1C, Fig.1D, Fig.1J

 

Fig.1F_GCEPIA1er.tif

Confocal image (green channel, G-CEPIA1er) for Fig. 1F

 

Fig.1F_TH.tif

Confocal image (blue channel, anti-TH immunostaining) for Fig. 1F

 

Fig.1G_GCEPIA1er.tif

Confocal image (green channel, G-CEPIA1er) for Fig. 1G

 

Fig.1G_CRT.tif

Confocal image (magenta channel, anti-CRT immunostaining) for Fig. 1G

 

Fig.1H_GCEPIA1er.tif

Confocal image (green channel, G-CEPIA1er) for Fig. 1H

 

Fig.1H_TH.tif

Confocal image (blue channel, anti-TH immunostaining) for Fig. 1H

 

Fig. 2B_mitoGCaMP6.tif

Confocal image (green channel, mito-GCaMP6) for Fig. 2B

 

Fig.2B_TH.tif

Confocal image (blue channel, anti-TH immunostaining) for Fig. 2B

 

Fig. 2C_mitoGCaMP6.tif

Confocal image (green channel, mito-GCaMP6) for Fig. 2C

 

Fig.2C_COXIV.tif

Confocal image (magenta channel, anti-COXIV immunostaining) for Fig. 2C

 

Fig. 2D_mitoGCaMP6.tif

Confocal image (green channel, mito-GCaMP6) for Fig. 2D

 

Fig.2D_TH.tif

Confocal image (blue channel, anti-TH immunostaining) for Fig. 2D

 

Fig.2FGJL.xlsx

Numerical data for the charts in Fig. 2F, Fig.2G, Fig.2J, Fig.2L

 

Fig.3BDE.xlsx

Numerical data for the charts in Fig. 3B, Fig.3D, Fig.3E

 

Fig.3C_Alexa.tif

MAX Projection of z-stack of 2PLSM images (magenta channel, Alexa 594 dye) used to generate Fig.3C top panel

 

Fig.3C_mitoGCaMP6.tif

MAX Projection of z-stack of 2PLSM images (green channel, mito-GCaMP6) used to generate Fig.3C top panel

 

Fig.3C_inset_dendritic_mitoGCaMP6.tif

2PLSM image (green channel, mito-GCaMP6) for Fig.3C bottom left panel

 

Fig.3C_inset_soma_mitoGCaMP6.tif

2PLSM image (green channel, mito-GCaMP6) for Fig.3C bottom right panel

 

Fig. 4A_PercevalHR.tif

Confocal image (green channel, PercevalHR) for Fig.4A

 

Fig.4A_TH.tif

Confocal image (blue channel, anti-TH immunostaining) for Fig.4A

 

Fig. 4B_PercevalHR.tif

Confocal image (green channel, PercevalHR) for Fig.4B

 

Fig.4B_TH.tif

Confocal image (blue channel, anti-TH immunostaining) for Fig.4B

 

Fig.4G.xlsx

Numerical data for the charts in Fig.4G

 

Fig.5BDFHI.xlsx

Numerical data for the charts in Fig.5B, Fig.5D, Fig.5F, Fig.5H, Fig.5I

 

Fig.6ADEFJKLN.xlsx

Numerical data for the charts in Fig.6A, Fig.6D, Fig.6E, Fig.6F, Fig.6J, Fig.6K, Fig.6L, Fig.6N

 

Fig.6H_mitoroGFP.tif

2PLSM image (green channel, mito-roGFP) for Fig.6H

 

Fig.6M_MCU-KO.tif

Combined EM micrographs used to generate Fig. 6M right side

 

Fig.6M_wildtype.tif

Combined EM micrographs used to generate Fig. 6M left side

 

Fig.7CEFG.xlsx

Numerical data for the charts in Fig.7C, Fig.7E, Fig.7F, Fig.7G

 

Fig.8CEHJK.xlsx

Numerical data for the charts in Fig.8C, Fig.8E, Fig.8H, Fig.8J, Fig.8K

 

Fig.S1A_bottom.tif

2PLSM image (green channel, G-CEPIA1er) for Fig.S1A bottom panel (low Ca2+)

 

Fig.S1A_top.tif

2PLSM image (green channel, G-CEPIA1er) for Fig.S1A top panel (high Ca2+)

 

Fig.S1B.xlsx

Numerical data for the chart in Fig.S1B

 

Fig.S2A_baseline.tif

2PLSM image (green channel, mito-GCaMP6) for Fig.S2A middle panel (baseline)

 

Fig.S2A_MAX.tif

2PLSM image (green channel, mito-GCaMP6) for Fig.S2A top panel (high Ca2+)

 

Fig.S2A_min.tif

2PLSM image (green channel, mito-GCaMP6) for Fig.S2A bottom panel (low Ca2+)

 

Fig.S2C_baseline.tif

2PLSM image (green channel, mito-GCaMP6) for Fig.S2C middle panel (baseline)

 

Fig.S2C_MAX.tif

2PLSM image (green channel, mito-GCaMP6) for Fig.S2C top panel (high Ca2+)

 

Fig.S2C_min.tif

2PLSM image (green channel, mito-GCaMP6) for Fig.S2C bottom panel (low Ca2+)

 

Fig.S2E_baseline.tif

2PLSM image (green channel, mito-GCaMP6) for Fig.S2E bottom left panel (baseline)

 

Fig.S2E_end.tif

2PLSM image (green channel, mito-GCaMP6) for Fig.S2E bottom right panel

 

Fig.S2E_peak.tif

2PLSM image (green channel, mito-GCaMP6) for Fig.S2E bottom center panel

 

Fig.S2F.xlsx

Numerical data for the chart in Fig.S2F

 

Fig.S3ABC.xlsx

Numerical data for the charts in Fig.S3A, Fig.S3B, Fig.S3C

 

Fig.S4CD.xlsx

Numerical data for the charts in Fig.S4C, Fig.S4D

 

Fig.S5ABC.xlsx

Numerical data for the charts in Fig.S5A, Fig.S5B, Fig.S5C

 

Fig.S7A.tif

2PLSM image (green channel, GCaMP6) for Fig.S7A

 

Fig.S7CEFGH.xlsx

Numerical data for the charts in Fig.S7C, Fig.S7E, Fig.S7F, Fig.S7G, Fig.S7H

 

Fig.S8ABCDEF.xlsx

Numerical data for the charts in Fig.S8A, Fig.S8B, Fig.S8C, Fig.S8D, Fig.S8E, Fig.S8F

 

Fig.S9AHIJK.xlsx

Numerical data for the charts in Fig.S9A, Fig.S9H, Fig.S9I, Fig.S9J, Fig.S9K

 

Fig.S9B_wildtype_DLStr.tif

Confocal image of dorso-laterateral striatum in wildtype mouse (red channel, anti-TH immunostaining) for Fig.S9B

 

Fig.S9C_MCU-KO_DLStr.tif

Confocal image of dorso-laterateral striatum in MCU-KO mouse (red channel, anti-TH immunostaining) for Fig.S9C

 

Fig.S9D_wildtype_SN.tif

Confocal image of midbrain in wildtype mouse (red channel, anti-TH immunostaining) for Fig.S9D

 

Fig.S9E_MCU-KO_SN.tif

Confocal image of midbrain in MCU-KO mouse (red channel, anti-TH immunostaining) for Fig.S9E

 

Fig.S9F_wildtype_openfield.png

Open field path tracked for wildtype mouse for Fig.S9F

 

Fig.S9G_MCU-KO_openfield.png

Open field path tracked for MCU-KO mouse for Fig.S9G

 

Fig.S10A.xlsx

Numerical data for the charts in Fig.S10A