Poster Open Access
Crystallization and structural characterization of triplexes and triplexligand systems using DNA X-ray crystallography
Abdullrahman, Ahmad; Dalla Pozza, Maria; Lambert, Megan C.; McQuaid, Kane; Cardin, Christine J.; Hall, James
The DNA triplex can be formed by the introduction of a triplex-forming oligonucleotide (TFO) to a DNA duplex. Here we show results describing the behaviour of triple helical molecules in UV-visible and circular dichroism spectroscopy. Additionally, we present the DNA structure obtained with X-Ray crystallography of a dsDNA belonging to a studied triplex DNA system.
Files
(1.2 MB)
| Name | Size | |
|---|---|---|
|
Poster_NAF220704.pdf
md5:c5b23f1a9aa2fdbc95bee4ed0d495cfe |
1.2 MB | Download |
22
25
views
downloads
| All versions | This version | |
|---|---|---|
| Views | 22 | 22 |
| Downloads | 25 | 25 |
| Data volume | 29.9 MB | 29.9 MB |
| Unique views | 22 | 22 |
| Unique downloads | 23 | 23 |
Indexed in
- Publication date:
- July 8, 2022
- DOI:
-
- Grants:
-
European Commission:
- NATURE-ETN - Nucleic Acids for Future Gene Editing, Immunotherapy and Epigenetic Sequence Modification (861381)
- Meeting:
- 18th RSC Nucleic Acids Forum, London, UK, 8 July 2022
- License (for files):
- Creative Commons Attribution 4.0 International