Published July 22, 2022 | Version v1
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Global Phosphoproteomics Unveils Kinase-regulated Networks in Systemic Lupus Erythematosus

Creators

  • 1. 1Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, P.R. China. 2Department of Rheumatology and Immunology, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, P.R. China.

Description

by combining high-throughput phosphoproteomics with bioinformatics approaches, we established the global phosphoproteome landscape of the peripheral blood mononuclear cells (PBMCs) from a large number of SLE patients including the remission stage (SLE_S), active stage (SLE_A), rheumatoid arthritis (RA), and healthy controls (HC). Processed data and code used for each figure has been  included.

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