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Published April 11, 2022 | Version v1
Poster Open

Mechanistic modelling of microbial communities with insights from an in vitro pig gut model

  • 1. School of Veterinary Medicine, University of Surrey, Guildford, UK
  • 2. School of Veterinary Medicine, University of Surrey, Guildford; School of Biosciences and Medicine, University of Surrey, Guildford, UK

Description

The gut microbiota play a key role in the health of animals and humans. However, the dynamic properties and stability of the microbiota are poorly understood. We propose a regression technique for parameter inference of a mechanistic model to describe the temporal dynamics of these microbial communities. The model could be used for measuring community resilience against external perturbing factors, such as antibiotic therapy.

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OHEJP 2022_FED_AMR_Brian.pdf

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Additional details

Funding

One Health EJP – Promoting One Health in Europe through joint actions on foodborne zoonoses, antimicrobial resistance and emerging microbiological hazards. 773830
European Commission