Published July 8, 2022
| Version v0.02
Journal article
Open
Computational modelling and near-complete kinetochore tracking reveal how chromosome dynamics during cell division are co-ordinated in space and time
Description
Dataset of Human RPE1 cells expressing Ndc80-eGFP imaged via lattice light sheet microscopy (LLSM) at high temporal resolution (2.05s per z stack) over long timescales (up to 15 mins). To accompany Harrison et al, 2022, "Computational modelling and near-complete kinetochore tracking reveal how chromosome dynamics during cell division are co-ordinated in space and time" https://doi.org/10.1101/2021.12.16.472953
Notes
Added .csv files containing tracks obtained via KiT (https://doi.org/10.5281/zenodo.6806435)
Files
OS_LLSM_200818_MC191_Untreated_capture1.ome.tif
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Additional details
Funding
- Kinetochore life-histories: understanding the mechanical events that ensure error-free chromosome segregation BB/R009503/1
- UK Research and Innovation
- Probing intra-cellular dynamics with lattice light sheet microscopy 208384
- Wellcome Trust
- KINETOCHORES AS FORCE SENSING AND GENERATING MACHINES. 106151
- Wellcome Trust