Published July 8, 2022
| Version 1.0.0
Dataset
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Integrative structure determination of PTBP1-viral IRES complex in solution
Creators
- Dorn, Georg1
- Gmeiner, Christoph1
- de Vries, Tebbe1
- Dedic, Emil1
- Novakovic, Mihajlo1
- Damberger, Fred F.1
- Maris, Christoph1
- Finol, Esteban1
- Sarnowski, Chris P.1
- Kohlbrecher, P.2
- Welsh, Timothy J.1
- Bolisetti, Sreenath1
- Mezzenga, Raffaele1
- Aebersold, Rudi1
- Leitner, Alexander1
- Yulikov, Maxim1
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Jeschke, Gunnar1
- Allain, Frédéric H.-T.1
- 1. ETH Zurich
- 2. Paul Scherrer Institut
Description
Data underlying the ensemble structure model of the RNA-binding protein PTBP1 in complex with the internal ribosome entry site (IRES) of encephalomyocarditis virus (EMCV) RNA.
- Primary DEER-EPR data underlying site-to-site distance distributions for 35 spin-label pairs and corresponding distanace distributions
- Small-angle neutron scattering (SANS) curves a two detector distances with corresponding resolution files and a small-angle x-ray scattering (SAXS) curve
- Restraint file for the ensemble fit with MMMx software, specifying the mean distances and standrad deviations of distance distributions that were also used for specifying lower and upper distance bounds in CYANA generation of the raw ensemble
Files
Deer_primary_and_distributions.zip
Additional details
Funding
- NMR structure determination of protein-RNA complexes involved in pre-mRNA splicing and translation regulation 31003A_149921
- Swiss National Science Foundation