Published June 24, 2022
| Version 1
Journal article
Open
β subunits of GABAA receptors form proton-gated chloride channels: Insights into the molecular basis
Creators
- 1. University of Vienna
- 2. Medical University of Vienna
Description
Supplemental material to the study "β subunits of GABAA receptors form proton-gated chloride channels: Insights into the molecular basis", published in Communications Biology.
The upload contains the raw electrophysiology data as well as Molecular Dynamics simulation data. Two simulations systems were created containing the GABAA channel harbouring a protonated and deprotonated H267, respectively. For each system, a compressed Gromacs trajectory containing the concatenated MD data (.xtc), a representative conformation (.pdb) and a .tpr file have been uploaded.
Files
Files
(2.1 GB)
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md5:a8139b2b5f20a04386a05e768bcb800a
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15.7 kB | Download |
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md5:500f3952c0a37ba72716bb2873e4f398
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20.9 MB | Download |
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md5:6e2b225117d3192b2d53d74bda498a83
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15.0 MB | Download |
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md5:9bf49cd8241c08477f5016bae89082e5
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994.0 MB | Download |
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md5:3b9bec17a3bc8de22ddde866f1876192
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20.9 MB | Download |
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md5:74dad8d0286d8fffd5ce7681756d2d38
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15.0 MB | Download |
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md5:8c3f45502e666a3e692aeebbdfd55b14
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988.8 MB | Download |
Additional details
Funding
- Molecular Drug Targets W 1232
- FWF Austrian Science Fund
- A research platform for the pre-clinical development of future peptide drug candidates ZK 81
- FWF Austrian Science Fund