First update - Priority List of Adverse Events of Special Interest: COVID-19

CEPI has contracted with the Brighton Collaboration, through the Task Force for Global Health, to harmonize the safety assessment of CEPI-funded vaccines via its Safety Platform for Emergency vACcines (SPEAC) Project. A key aspect of this harmonization has been creation of lists of priority potential adverse events of special interest (AESI) that are relevant to vaccines targeting CEPI target diseases.

The primary objective is to present the first quarterly update for the COVID-19 AESI priority list. A detailed description of changes to the ongoing search strategy is included. This was necessitated by the huge volume of new publications on all aspects of COVID-19 spread, clinical presentation, complications, treatment and prevention.