Published July 31, 2022
| Version v1
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PD1+CD8+ cells are an independent prognostic marker in patients with head and neck cancer
Authors/Creators
- 1. Department of Genetics and Microbiology, Faculty of Science, Charles University, BIOCEV, 252 50 Vestec, Czech Republic
- 2. Department of Pathology and Molecular Medicine, 2nd Faculty of Medicine, Charles University, 150 06 Pra-gue, Czech Republic
- 3. Department of Otorhinolaryngology and Head and Neck Surgery, 1st Faculty of Medicine, Charles University, University Hospital Motol, 150 06 Prague, Czech Republic
- 4. Department of Mathematical Analysis and Applications of Mathematics, Faculty of Science of the Palacky University in Olomouc, 771 46 Olomouc, Czech Republic
Description
Supplementary Materials: The following supporting information can be downloaded at: www.mdpi.com/xxx/s1,
Table S1. Reaction conditions for each panel of antibodies. The order of antibodies and buffer used for epitope retrieval (AR) are indicated as well as the reaction conditions for the primary antibody and OPAL fluorophore staining. For all slides, Opal Polymer HRP Ms+Rb as the secondary antibody and DAPI as the final nuclei counterstain were used.
Table S2. Cell counts/Mpx in the parenchyma and stroma of HNSCC tumors
Table S3: Models of DSS and OS.
Data open: file with parametres used for the multivariate evaluation.
Notes
Funding: This research was funded by the Czech Health Research Council, grant number 17-28055A; and the European Regional Development Fund and the Ministry of Education, Youth and Sports of the Czech Republic, grant number CZ.02.1.01/0.0/0.0/16_019/0000785, by the project National Institute of Virology and Bacteriology (Programme EXCELES, ID Project No. LX22NPO5103) - Funded by the European Union - Next Generation EU, and by the Charles University, grant number SVV 260568.
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