Published December 6, 2021
| Version 3
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Synthesis and characterization of some new heterocyclic compounds from α, β- unsaturated carbonyl system
Creators
- 1. Analytical and pharmaceutical chemistry Department, Faculty of pharmacy, Omar Al-Mukhtar University, El -Beida-Libya
- 2. Chemistry Department, Faculty of Science, Omar El – Mukhtar University, Libya
Description
An efficient and facile one pot synthesis of 3,4-dihydropyrimidinones (Belinelli compound) from furfural, acetylacetone and urea under solvent free conditions was performed, resulted in promising yield. These compounds reacted with benzaldehyde and furfural to give the corresponding chalcones. Chalcones are used to synthesize several derivatives like pyrazolines isoxazoles and pyrimidines having different heterocyclic ring systems.
https://www.raftpubs.com/ojpsr-pharmaceutical-science-and-research/articles/ojpsr_raft1015.php
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