Published June 1, 2022
| Version 1
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Supplementary Data for "Epigenetic mechanisms controlling human leukemia stem cells and therapy resistance"
Description
We performed functional genomic profiling of diverse leukemias using label tracing techniques. We identified AML stem cell quiescence is defined by distinct promoter-centered chromatin and gene expression dynamics, and controlled by a novel transcription factor network, which is associated with disease persistence and chemotherapy resistance in multiple patients.
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Zenodo_AMLstem_AKlab_220601.zip
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(12.9 MB)
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