Supplementary 2: Laminin-5 is localized in areas with high filopodia density.

Cells were seeded on coverslips and stained for DAPI (grey), laminin-5 (blue), F-actin with phalloidin (green), and virus (red). Confocal images on left side are cells not incubated with PsVs. Cells treated with (A-E) no drug, (F-J) 200 ng/mL bradykinin for 15 minutes, (K-O) 200 ng/mL EGF for 15 minutes, (P-T) 10 µM ML-141 for 2 hours. On right side cells were incubated with virus, (U-Y) control infection, (Z-DD) 200 ng/mL bradykinin for 15 minutes, (EE-II) 200 ng/mL EGF for 15 minutes, (JJ-NN) 10 µM ML-141 for 2 hours. Laminin-5 (blue) and PsVs (red) overlap appears magenta.S2: Laminin-5 is localized in areas with high filopodia density. Cells were seeded on coverslips and stained for DAPI (grey), laminin-5 (blue), F-actin with phalloidin (green), and virus (red). Confocal images on left side are cells not incubated with PsVs. Cells treated with (A-E) no drug, (F-J) 200 ng/mL bradykinin for 15 minutes, (K-O) 200 ng/mL EGF for 15 minutes, (P-T) 10 µM ML-141 for 2 hours. On right side cells were incubated with virus, (U-Y) control infection, (Z-DD) 200 ng/mL bradykinin for 15 minutes, (EE-II) 200 ng/mL EGF for 15 minutes, (JJ-NN) 10 µM ML-141 for 2 hours. Laminin-5 (blue) and PsVs (red) overlap appears magenta.