Published July 30, 2019 | Version v1
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Meta-analysis on vitamin C and the common cold in children may be misleading

  • 1. University of Helsinki, Finland
  • 2. Australian National University, Australia

Description

This report describes severe problems in the meta-analysis on vitamin C and the common cold:

Vorilhon P, Arpajou B, Vaillant Roussel H, Merlin É, Pereira B, Cabaillot A. Efficacy of vitamin C for the prevention and treatment of upper respiratory tract infection. A meta-analysis in children. Eur J Clin Pharmacol. 2019 Mar;75(3):303-311. doi: 10.1007/s00228-018-2601-7.

Further problems in that meta-analysis are described in: https://hdl.handle.net/10138/333365.

The meta-analysis by Vorilhon et al. was later retracted:

Vorilhon P, Arpajou B, Roussel HV, Merlin É, Pereira B, Cabaillot A. Retraction Note: Efficacy of vitamin C for the prevention and treatment of upper respiratory tract infection. A meta-analysis in children. Eur J Clin Pharmacol. 2021 Jun;77(6):941. doi: 10.1007/s00228-021-03150-9.

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Is continued by
Report: 10138/333365 (Handle)
Is identical to
Report: https://static-content.springer.com/esm/art%3A10.1007%2Fs00228-019-02733-x/MediaObjects/228_2019_2733_MOESM1_ESM.pdf (URL)
Is supplement to
Journal article: 10.1007/s00228-019-02733-x (DOI)
Reviews
Journal article: 10.1007/s00228-018-2601-7 (DOI)