Synthesis of New 5-Substituted Pyrazolinyl Oxazolophenoxazine Derivatives

Chemistry Department, Faculty of Science, Assiut University, Assiut, Egypt, A.R.E

Manuscript received 18 June 1976, revised 14 October 1976, accepted 19 November 1976

Substituted cinnamoyl chloride (1) reacted with 2-aryl-5H-oxazolo(4,5-b) phenoxazines in dioxane in the presence of triethylamine to give 5-substituted benzalacetyl oxazolophenoxazine derivatives (III). (III) reacted easily with hydrazine hydrate, phenyl hydrazine and hydroxyla­mine giving the corresponding pyrazolines and isozazolines respectively.