Sodium Dodecyl Sulphate (NaLS) Inhibition of the Nucleophilic Substitution Reaction Between Phenacyl Bromide and Aliphatic Carboxylates

P. G. Department of Chemistry, Sambalpur University, Jyoti Vihar, Burla-768 017

Manuscript received 20 November 1980, revised 12 August 1981, accepted 6 November 1981

The effect of varying concentration of sodium dodecyl sulphate (NaLS) as an anionic surfactant micelle has been studied on the reaction of  phenacyl bromide and aliphatic carboxylates in 72 : 28 acetone-water mixture. The second order rate constant (k₂) decreases with increasing concentration of NaLS. The surfactant concentration has been maintained above the critical micelle concentration (cmc) value in the aqueous organic medium. The rate constants in two different solvent compositions have been compared. The activation parameters have been computed in the cases of two different carboxylates and discussed.