Published June 22, 2021
| Version v1
Journal article
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Benefits in the Macrophage Response Due to Graphene Oxide Reduction by Thermal Treatment
Creators
- 1. Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain
- 2. Center for Mechanical Technology & Automation (TEMA), Mechanical Engineering Department, University of Aveiro, 3810-193 Aveiro, Portugal
- 3. Departamento de Microbiología y Parasitología, Facultad de Farmacia, Universidad Complutense de Madrid, 28040 Madrid, Spain
Description
Response of RAW-264.7 macrophages to graphene oxide (GO) and two types of reduced GO, rGO15 and rGO30, obtained after thermal treatment of 15 and 30 min, respectively. Analysis of the uptake of these nanostructures, the intracellular content of reactive oxygen species, and specific markers of the proinflammatory M1 phenotype, such as CD80 expression and secretion of inflammatory cytokines TNF-α and IL-6.
Notes
This work was supported by the European Horizon 2020 - FET OPEN Program under Grant No. 829060 ("NeuroStimSpinal"; URL: www.neurostimspinal.eu/")
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- https://www.neurostimspinal.eu/ (URL)