Published March 23, 2014 | Version v1
Journal article Open

ASSOCIATION BETWEEN BENIGN PROSTATIC HYPERPLASIA AND URINARY TRACT INFECTION

  • 1. Department of Medical Microbiology and Parasitology, Basic Medical Sciences, College of Health Sciences, University of Ilorin, Ilorin, Nigeria
  • 2. Urology Clinic, Surgical Out Patient Department, University of Ilorin Teaching Hospital, Ilorin, Nigeria
  • 3. Medical Microbiology and Parasitology Laboratory, University of Ilorin Teaching Hospital, Ilorin, Nigeria

Description

Benign prostatic hyperplasia is a progressive condition characterized by prostate enlargement. It has an estimated prevalence of 50% in men aged 50-60 and 90% in men over 80 years. Scottish Intercollegiate Guidelines Network, using urodynamic techniques, revealed significant underlying lower urinary tract abnormalities, mainly involving bladder out flow obstruction in 80% of adult males presenting with simple or recurrent urinary tract infection. Mid stream urine samples were collected from 94 BPH patients and 94 age-matched non BPH patients. Samples were processed within one hour of production. Based on evidence of pyuria on wet preparation and significant bacteriuria on culture, samples were considered to be positive for UTI.UTI prevalence was higher among BPH patients (33.0%) than their control (23.4%). Odd ratio 0.33 with p-value 0.2 was obtained for ages 50-59 while odd ratio 4.4 with p-value 0.03 was obtained for ages 80 and above. Prevalence of UTI was higher among BPH patients than men without BPH. Significant association between BPH and UTI was found among ages 80 years and above.

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