Studies on Potential Pesticides. Part XIII : Synthesis and Evaluation of S-(3-Substituted Phenoxymethyl-4-Aryl/Cyclohexyl-4H-1,2,4-Triazol-5-yl)-2-Mercaptomethyl Benzimidazoles for Antibacterial and Insecticidal Activities

Department of Chemistry, Lucknow University, Lucknow-226 007

Manuscript received 12 December 1979, revised 11 November 1980, accepted 10 March 1981

A number of benzimidazole derivatives were synthesized from S-[3-(substituted phenoxymethyl)-4-aryl/cyclohexyi-4H-1,2,4-triazol-5-yl]-mercaptoacetic acids by con- densation with o-phenylenediamine in presence of 4N hydrochloric acid. The N¹- (substituted phenoxyacetyl)-N⁴ -aryl/cyclohexyl-3-thiosemicarbazides, 3-(substituted phenoxymethyl)-4-aryl/cyclohexyl-5-mercapto 1, 2, 4-triazoles and S-[3-(substituted phenoxymethyl)-4-aryl/cyclohexyl-4H-1,2,4-triazol-5-yl]·mercaptoacetic acids were also synthesized. All the new compounds were screened for antibacterial and insecticidal activities. Most of these were found to possess significant antibacterial and insecticidal activities. Relationship between their biocidal character and chemical structure has been studied.