Published November 17, 2021
| Version 2
Dataset
Open
Characterizing and explaining impact of disease-associated mutations in proteins without known structures or structural homologues
Creators
- 1. University College London
- 2. University of Washington
- 3. EMBL-EBI
Description
AlphaFold and RoseTTAFold models of domains of disease associated human proteins without structures/known homologues.
Tables containing the model quality, model region, sequence alignment statistics, matched FunFam, associated GO terms for the FunFam, ddG of mutation, pathogenicity of mutation, if mutation is near a predicted functional site (conserved residue/ligand binding site/protein-protein interface)
Files
Files
(5.0 GB)
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md5:dcf8de17812118350b3c863702d2d14e
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35.5 MB | Download |
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399.8 kB | Download |
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253.1 kB | Download |
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40.1 kB | Download |
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md5:bbac8e1464cad6c5fb6a914d50d8bc3c
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5.0 GB | Download |