Acute Kidney Injury in a Young Patient with Severe Malaria: A Case Report
- 1. Department of Internal Medicine, Mogadishu Somalia-Turkey Recep Tayyip Erdoğan Training and Research Hospital, University of Health Sciences, Mogadishu, Somalia.
- 2. Department of Internal Medicine, Adana City Training and Research Hospital, University of Health Sciences, Turkey.
Description
Abstract
Acute kidney injury is a complication of severe malaria that is relatively uncommon. It has clinical importance associated with substantial morbidity and mortality in malaria-endemic regions. We report a young patient who developed acute renal injury as a result of severe malaria. In this case, malaria diagnosis was confirmed using the malaria rapid screening test and microscopic inspection of blood smears. Fever, nausea and vomiting, loss of appetite and jaundice were the clinical presentations. Treatment with artemether injection, volume expansion and antipyretics was given. He recovered well without needing hemodialysis. This is not always the case, and the prognosis is dependent on the time of presentation, the diagnosis, and the treatment received.
Özet
Akut böbrek hasarı, ciddi sıtmanın nispeten nadir görülen bir komplikasyonudur. Sıtmanın endemik olduğu bölgelerde morbidite ve mortalite ile ilişkili klinik önemi vardır. Şiddetli sıtma nedeniyle akut böbrek hasarı gelişen genç bir hasta olgusunu sunuyoruz. Bu olguda, sıtma tanısı sıtma hızlı tarama testi ve kan yaymalarının mikroskobik incelemesi ile doğrulandı. Klinik prezentasyonlar ateş, bulantı ve kusma, iştahsızlık ve sarılıktı. Artemeter enjeksiyon ile tedavi edilen hastaya volüm desteği ve antipiretik verildi. Hasta hemodiyaliz gereksinimi olmaksızın iyileşti. Olgularda durum her zaman böyle değildir ve prognoz başvuru zamanına, tanıya ve alınan tedaviye bağlıdır.
Notes
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References
- 1. Muse Osman M, Abdullahi Ali M, Bashir AM, Nur Adan F, Sümbül HE, Sherani MH, et al. Investigation of the Annual and Periodic Distribution of Malaria Cases in Mogadishu, Somalia: A Retrospective Analysis of Four-Year Data. Life Med Sci 2022; 1(2): 47-54.
- 2. Larson B. Origin of Two Most Virulent Agents of Human Malaria: Plasmodium falciparum and Plasmodium vivax (Chapter). In: Kasenga FH (ed), Malaria - Infectious Diseases (Volume 4). 2019, In Tech Open, London. pp:1-16.
- 3. World Health Organization (WHO), Geneva, Switzerland. World Malaria Report 2021. Available at: https://www.who.int/teams/global-malaria-programme/reports/world-malaria-report-2021 [Accessed December 6, 2021].
- 4. Lover AA, Baird JK, Gosling R, Price RN. Malaria Elimination: Time to Target All Species. Am J Trop Med Hyg 2018; 99(1): 17-23.
- 5. Milner DA Jr. Malaria Pathogenesis. Cold Spring Harb Perspect Med 2018; 8(1): a025569.
- 6. Das BS. Renal failure in malaria. J Vector Borne Dis 2008; 45(2): 83-97.
- 7. Vannaphan S, Walters N, Saengnedsawang T, Tangpukdee N, Kham-In P, Klubprasit M, et al. Factors associated with acute renal failure in severe falciparum [corrected] malaria patients. Southeast Asian J Trop Med Public Health 2010; 41(5): 1042-7. Erratum in: Southeast Asian J Trop Med Public Health 2010; 41(6): 1512.
- 8. Nguansangiam S, Day NP, Hien TT, Mai NT, Chaisri U, Riganti M, et al. A quantitative ultrastructural study of renal pathology in fatal Plasmodium falciparum malaria. Trop Med Int Health 2007; 12(9): 1037-50.
- 9. Badiane AS, Diongue K, Diallo S, Ndongo AA, Diedhiou CK, Deme AB, et al. Acute kidney injury associated with Plasmodium malariae infection. Malar J 2014; 13: 226.
- 10. Prakash J, Gupta A, Kumar O, Rout SB, Malhotra V, Srivastava PK. Acute renal failure in falciparum malaria--increasing prevalence in some areas of India--a need for awareness. Nephrol Dial Transplant 1996; 11(12): 2414-6.
- 11. Meremo AJ, Kilonzo SB, Munisi D, Kapinga J, Juma M, Mwanakulya S, et al. Acute renal failure in a Caucasian traveler with severe malaria: a case report. Clin Case Rep 2014; 2(3): 82-5.
- 12. Barsoum RS. Malarial acute renal failure. J Am Soc Nephrol 2000; 11(11): 2147-54.
- 13. Gowda S, Desai PB, Shetty SJ, Kagwad VS, Ilakal MB. Malarial hepatitis and renal failure: a study of two cases. Italian Journal of Public Health 2012; 8(1): 19-21.
- 14. Mishra SK, Das BS. Malaria and acute kidney injury. Semin Nephrol 2008; 28(4): 395-408.