Studies on Biologically Active Heterocycles. Part-III. Synthesis and Antibacterial Activity of some 2-Aryl/ Aralkyl-3-substituted-4-thiazolidinones

Regional Research Laboratory, Jorhat-785 006

Manuscript received 30 January 1989, revised 24 July 1989, accepted 21 November 1989

A series of new 2-aryl/aralkyl-3-[2,4·dichlorobenzamido]-4-thiazolidinones and 2-aryl/aralkyl-3-[2-chlorobenzamido]-4-thiazolidinones have been synthesised by con- densation of the respective hydrazones with mercaptoacetic acid. The hydrazones have been prepared by condensing different aromatic and aliphatic aldehydes with the corresponding acylhydrazides. All the compounds were screened for their antibacterial activity.