Supplementary Dataset S8 for publication "Universality in human cortical folding in health and disease"
The data sources and method of extracting the data are described in the publication "Universality in human cortical folding in health and disease". PNAS 2016
2019 update: The matlab code for extraction of relevant variables from Freesurfer subjects is now published on Zenodo and Github.
We used four publicly available datasets in this study.
The HCP dataset has been obtained from 500 subjects release from the Human Connectome Project (www.humanconnectome.org). Data were provided in part by the Human Connectome Project, WU-Minn Consortium (Principal Investigators: David Van Essen and Kamil Ugurbil; 1U54MH091657) funded by the 16 NIH Institutes and Centers that support the NIH Blueprint for Neuroscience Research; and by the McDonnell Center for Systems Neuroscience at Washington University.
The OASIS data has been obtained from the Open Access Series of Imaging Studies project (www.oasis-brains.org). We used the cross-sectional dataset, and only included the subset of healthy subjects. OASIS project was supported by P50 AG05681, P01 AG03991, R01 AG021910, P50 MH071616, U24 RR021382, R01 MH56584.
The NKI data has been obtained from Nathan Kline Institute (NKI) Rockland Sample (http://fcon_1000.projects.nitrc.org/indi/pro/nki.html), where funding for key personnel was provided in part by the New York State Office of Mental Health and Research Foundation for Mental Hygiene. Additional project support provided by the NKI Center for Advanced Brain Imaging (CABI), the Brain Research Foundation (Chicago, IL), the Stavros Niarchos Foundation, and NIH grant P50 MH086385-S1.
The ADNI data has been obtained from the Alzheimer's Disease Neuroimaging Initiative (http://adni.loni.usc.edu/). Data collection and sharing for the ADNI project was supported by ADNI (National Institutes of Health Grant U01 AG024904).
We included subjects from ADNI1, ADNI GO, and ADNI2, and selected all 3T sessions. For all subjects we only included one scan point (first 3T scan), to be consistent with the previous three cross-sectional datasets. We also only included the healthy controls and the Alzheimer's patients in this study.
As we only used publicly available datasets, no informed consent procedure was required. We confirm that we complied with all the data usage policies of each of the datasets we used. A general ethical approval was granted by Newcastle University to carry out the described research under the reference number 1186/2015.