Dataset Open Access

Secretin-like class B G protein-coupled receptor (GPCR) mutation data set

de Graaf, Chris

Curated set of 2463 quantitative mutation data points covering 13 secretin-like class B G protein-coupled receptors.

Annotated according to GPCRdb standards (http://gpcrdb.org/), complemented by GPCRdb Ballesteros-Weinstein numbers assigned using GPCRdb KNIME nodes (https://github.com/3D-e-Chem/knime-gpcrdb).

The data set is build from data sets published in:

- Siu et al. Nature 2013, 499: 444-449. doi:10.1038/nature12393

- Hollenstein, de Graaf et al. Tr Pharmacol Sci 2014, 35: 12-22. doi: 10.1016/j.tips.2013.11.001

- Yang, de Graaf et al. J Biol Chem 2016, 291: 12991-3004. doi: 10.1074/jbc.M116.721977

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