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Published February 1, 2022 | Version v1
Dataset Open

Predicted gene expression in ancestrally diverse populations leads to discovery of susceptibility loci for lifestyle and cardiometabolic traits

  • 1. University of North Carolina at Chapel Hill

Description

Full summary statistics for the publication "Predicted gene expression in ancestrally diverse populations leads to discovery of susceptibility loci for lifestyle and cardiometabolic traits". 

The files, bmi.UKBBsummary.txt and height.UKBBsummary.txt, contain tissue specific associations with body mass index (BMI) and height respectively. The suffix UKBB450k indicates results from all ~450,000 European ancestry individuals in UK Biobank. The suffix UKBB50k corresponds to results from a subset of 50,000 Europeans in the UK Biobank. The suffix PAGE corresponds to results from ~50,000 individuals in the Population Architecture using Genomics and Epidemiology (PAGE) study. 

The file PAGE_PrediXcan_associations.txt includes trait~tissue specific GReX associations for 25 traits. The first field specifies the tissue.trait.gene of the association results.

Files

bmi.UKBBsummary.txt

Files (675.5 MB)

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md5:f9841902599f4503969ba0c0c3058094
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md5:a8d81dbc4c200cc52c7ec68ab76027a9
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md5:64c7fd85e704a4edfc6d4f41767742a3
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Additional details

Related works

Is published in
Journal article: 10.1016/j.ajhg.2022.02.013 (DOI)