Viscosity B-Coefficients of some Known Drug Molecules (as Hydrochlorides) at 298 K

Department of Chemistry, University of Kalyani. Kalyani-741 235
Manuscript received 21 September 1993, revised 6 April 1994, accepted 29 April 1994

Viscosity B-coefficients of a number of drugs, viz. hydrochlorides of promethazine, chlorpromazine, papaverine, ephedrine, pseudoephedrine and isoxsuprine, in water have been determined, and found to be fairly high. The solvation numbers, single ion viscosity B-coefficients (B₊) show that the cations of promethazine, chlorpromazine and papaverine are highly solvated due to hydrophobic hydrations whereas other cations are relatively less solvated.