Published January 31, 2022
| Version v1
Journal article
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Megaviruses contain various genes encoding for eukaryotic vesicle trafficking factors
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Description
Giant viruses enter their eukaryotic host cells by phagocytosis. For reproduction, they hijack the host cell’s membranes of the host cell by an unknown mechanism. Here, we found that giant viruses express several core factors of the eukaryotic vesicle fusion machinery, including SNARE, Rab, SM proteins, and the disassembly protein NSF.
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Additional details
Funding
- Structural and evolutionary studies on the vesicle fusion machinery 31003A_182732
- Swiss National Science Foundation