Nickel chloride catalyzed arylation of 3-mercaptopropionic acid : a facile one step route to 3-aryl mercaptopropionic acids from unactivated aryl halides and arenes

Department of Chemistry, Govt. Postgraduate College. Kota. India
Department of Chemistry, Banasthali Vidyapith, Banasthali-304 022. India
E-mail : kishorcdharma@.yahoo.co.in      Fax: 91-1438-228365
Department of Chemistry, University of Rajasthan, Jaipur-302 004. India
Manuscript received 18 February 2003, revised 20 October 2003. accepted J 2 January 2004

Nickel chloride catalyzed arylation of 3-mercaptopropionic acid by (i) unactivatcd aryl halides (path a) and (ii) diphenyliodonium bromide (path b) gave 3-aryl mercaptopropionic acid (3) in good yield.