Journal article Open Access


Mrs. Jyotsnaa H Waggh, Miss. Sayali S. Erande

Antiviral are a class of drugs that are used to treat viral infections currently available antiviral infection. Currently available antiviral drugs target only main groups of viruses that are: herpes, hepatitis and influenza viruses most disease caused by viruses tend to end without treatment and do not require antiviral therapy. Acyclovir, Brivudine, Docosanol, Trifluridine, valacyclovir etc. are the examples of common antiviral drugs.

Due to viruses a wide range of human diseases causes, ranging from acute self-resolving conditions to acute fatal diseases. The propensity  for chronic conditions can also increase after the long arise of primary infection which may lead to the development of cancer. Our understanding of recent advances for viral pathogenesis, to improve vaccination strategies and developing the newer along with more effective treatment for patient in all over the world due to virology and pathology. The review has focus on interface in between virology and pathology and to hold the aspects of clinical pathology of viral disease and the mechanisms of disease underlying. The articles based on prominent diseases caused by viruses such as Ebola virus, Marburg virus, coronaviruses (SARS and MERS), Nipah virus and noroviruses are followed by reviews of enteroviruses, HIV infection, human respiratory syncytial virus (RSV), influenza, cytomegalovirus (CMV) and varicella zoster virus (VZV). The issue have been concluded with a series of articles by reviewing the relationship between viruses and cancer, including the role played by Epstein-Barr virus (EBV) in the pathogenesis of lymphoma and carcinoma; which reveal how human papillomaviruses (HPVs) are involved in the development of skin cancer as well as the involvement of hepatitis B virus infection in hepatocellular carcinoma; and the mechanisms with Kaposi's sarcoma-associated herpesvirus (KSHV) leads to Kaposi's sarcoma. Hopefully this collection of articles will help the scientists and clinicians at a time while there is a renaissance in the appreciation of the power of pathology as virologists dissect the processes of disease.

Keywords: CMV; EBV; HPV; KSHV; MERS; Marburg virus; RSV; SARS; VZV; coronavirus; enterovirus; measles.

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