Reliability and Validity of an Arabic Version of Quality of life - Alzheimer Disease in Alexandria, Egypt

Objectives: Quality of life has been currently recognized as a highly important outcome measure in the management of dementia. This work aimed to examine the psychometric properties of an Arabic-translation of Quality of life-Alzheimer Disease scale (QoL-AD) for patient and caregiver reports in Alexandria, Egypt. Methods: A total of 100 patient-caregiver dyads who attended the psycho-geriatric out-patient clinic of El-Mammora Mental Hospital in Alexandria participated in a cross sectional study. Tools included the Mini Mental State Examination (MMSE), Katz Index for Activities of Daily Living (ADL), the Patient Health Questionnaire-9 (PHQ-9), and the QoL-AD. Results: Both patients and caregivers reports showed satisfactory internal consistency (Cronbach’s alpha coefficient > 0.70). The correlation between patient and caregiver ratings was very good (Rho= 0.75, p≤ 0.001). All validity measures used (PHQ-9, ADL) revealed good convergent validity of the Arabic version. The principal component factor analysis supported the construct validity of the scale. Conclusion: The Arabic version of QoL-AD is a reliable and valid tool in people with dementia with a MMSE of 10 or higher.