Demographic, neuroradiological and neuropathological characteristics among children with central nervous system tumors in the iranian referral center for stereotaxis

Abstract

Introduction & Background. Central nervous system (CNS) tumors are common types of malignancies in children and the recognition of these tumors and related factors can help to improve the prognosis. The purpose of the present study was to evaluate demographic, neuroradiological, and neuropathological characteristics in 1-14-year-old children with central nervous system tumors in the Department of Pediatrics of Shohada-e Tajrish Hospital. Methods. In this descriptive study, 96 children aged 1-14 years with central nervous system tumors in the Department of Pediatrics of Shohada-e Tajrish Hospital from 2014 to 2016 were selected by convenience sampling, and the demographic, neuroradiological, and neuropathological characteristics were determined and compared according to other variables. Results. 60.4% of the patients were aged 1-10 years and 55.2% of them were male. The most common types of tumors were astrocytoma (33.3%), glioma (16.7%) and medulloblastoma (10.4%). 46.9% of the tumors were supratentorial and 53.1% were infratentorial. Enhancement was observed in 53.1% of the patients in imaging. Conclusion. Overall, based on the obtained results, it may be concluded that the most common types of CNS tumor in children are astrocytomas and these tumors are usually infratentorial with enhancement in imaging.