Synthesis and biological potential of nitrones of 4-chlorobenzaldehyde and ethylvanillin

Department of Chemistry, Department of Plant Pathology,

Punjab Agricultural University, Ludhiana-141 004, Punjab, India

Manuscript received 4 December 2006, revised 3 February 2009, accepted 11 February 2009

Nitrones of 4-chlorobenzaldehyde (1a-6a) and ethylvanillin (1b-6b) were synthesized by condensing 4- chlorobenzaldehyde (a) and ethylvanillin (b) with phenylhydroxylamines (1-6) in equimolar ratio. The synthesized nitrones were characterized on the basis of elemental analysis and spectral studies and screened for antifungal potential against six phytopathogenic fungi and nematicidal activity against two nematodes.