Published November 30, 2021 | Version v1
Dataset Open

Host and pathogen gene expression profiles in Necrotizing Soft Tissue Infections

  • 1. Wageningen Univeristy & Research

Description

Data underlying the article

Analysis of host-pathogen gene association networks reveals patient-specific response to streptococcal and poly-microbial necrotizing soft tissue infections

Sanjeevan Jahagirdar1, Lorna Morris2, Nirupama Benis3, Oddvar Oppegaard4, Mattias Svenson5, Ole Hyldegaard6, Steinar Skrede4,7, Anna Norrby-Teglund5, INFECT Study group, Vitor A. P. Martins dos Santos1,2, Edoardo Saccenti1*

Contains

Data described in 4.3.2 Sample Selection and in Figure 6:

INFECT_DualRNASeq_norm_counts_Human.txt  Normalised counts from Kallisto mapping to GRCh38 (release 91) for 81 NSTI patients

INFECT_DualRNASeq_relative_abundance_Bacteria.txt Relative abundance for all species from HumanN2 mapping for 81 NSTI patients

BStrep_filtered_D1 - INFECT_DualRNASeq_relative_abundance_Bacteria.txt filtered for samples classified as Streptococcal from Thänert et al (2019) taken on the day of admission (day 1).

BPoly_filtered_D1 - INFECT_DualRNASeq_relative_abundance_Bacteria.txt filtered for samples classified as polymicrobial from Thänert et al (2019) taken on the day of admission (day 1).

HStrep_filtered_D1 - INFECT_DualRNASeq_norm_counts_Human.txt filtered for samples classified as Streptococcal from Thänert et al (2019) taken on the day of admission (day 1).

HPoly_filtered_D1 - INFECT_DualRNASeq_norm_counts_Human.txt filtered for samples classified as polymicrobial from Thänert et al (2019) taken on the day of admission (day 1).

Files

BPoly_filtered_D1.csv

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Additional details

References

  • 10.1038/s41467-019-11722-8