Gates Foundation
Published February 1, 2021 | Version Accepted Version
Journal article Open

Fourteen-day PET/CT imaging to monitor drug combination activity in treated individuals with tuberculosis

Creators

  • 1. Division of Infectious Diseases, Department of Medicine, Rutgers New Jersey Medical School, Newark, NJ 07103, USA.
  • 2. TASK Applied Science, Cape Town 7500, South Africa.
  • 3. Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD 20892, USA.
  • 4. Biostatistics Research Branch, Division of Clinical Research, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD 20892, USA.
  • 5. Imaging Group, NET ESolutions Inc., McLean, VA 22102, USA.
  • 6. Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
  • 7. Department of Science and Technology—National Research Foundation Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town 7600, South Africa.
  • 8. Microbial Pathogenesis, Yale University, New Haven, CT 06520, USA.
  • 9. Catalysis Foundation for Health, San Ramon, CA 94583, USA.
  • 10. Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town 7925, South Africa.

Description

This is the accepted manuscript version of the work published in its final form as Xie, Y. L., de Jager, V. R., Chen, R. Y., Dodd, L. E., Paripati, P., Via, L. E., Follmann, D., Wang, J., Lumbard, K., Lahouar, S., Malherbe, S. T., Andrews, J., Yu, X., Goldfeder, L. C., Cai, Y., Arora, K., Loxton, A. G., Vanker, N., Duvenhage, M., … Barry, C. E. (2021). Fourteen-day PET/CT imaging to monitor drug combination activity in treated individuals with tuberculosis. Science Translational Medicine, 13(579). https://doi.org/10.1126/scitranslmed.abd7618.

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