Mono- and disubstituted aryldithiocarbonates of titanium(IV) and zirconium(IV)

Department of Chemistry, University of Jammu, Baba Sahib Ambedkar Road, Jammu-180 006,

Jammu & Kashmir, India

E-mail : kpsushil@rediffmail.com

Manuscript received online 11 February 2015, revised 09 April 2015, accepted 06 May 2015

New dithiocarbonates of titanium(IV) and zirconium(IV) corresponding to [(ROCS₂ )_nM(C₅H₅ )₂Cl_2-n] (R = o-, m- or p-CH₃C₆H₄ , and 4-Cl-3-CH₃C₆H₃ ; n = 1 or 2; M = Ti or Zr) have been isolated by the reaction of sodium salt of dithiocarbonates with titanocene or zirconocene dichloride in 1 : 1 and 1 : 2 molar ratio in CHCl₃ . These have been characterized by elemental analyses, mass, IR and heteronuclear NMR (¹H and ¹³C) spectroscopic analyses. Thermal and redox properties of complexes were studied by thermogravimetric analysis and cyclic voltammetry. Based on analytical results, penta- and hexa-coordinate geometries are concluded around the Ti or Zr atom. The antimicrobial test of these complexes has been conducted against the bacteria Klebsiella pneumonia and Enterococcus faciolus and fungus Rhizopus nigricans. The cytotoxic properties of the few ligands and complexes were also measured in vitro using the cultivated human cell lines.