PREDICT: a method for inferring novel drug indications with application to personalized medicine

The zip file include space-delimited similarity and interaction files:

Interactions and descriptors:

• commonAssociationMat - the binary indicators of drug-indication matrix (n drugs x m diseases)
• commonDiseasesSimilarity - the list of OMIM diseases (size m)
• commonDrugsSimilarity - the list of DrugBank IDs (size n)

Drug similarities

• chemicalDrugsCommonSimilarityMat - chemical similarity matrix (nxn matrix)
• pSideEffectDrugsCommonSimilarityMat - side effect similarity (nxn matrix)
• sdt_distDrugsCommonSimilarityMat -drug target PPI similarity (nxn matrix)
• sdt_GODrugsCommonSimilarityMat - drug target GO similarity (nxn matrix)
• sdt_seqDrugsCommonSimilarityMat - drug target sequence similarity (nxn matrix)

Disease similarities

• hpDiseasesCommonSimilarityMat - human phenotype similarity (mxm matrix)
• phenDiseasesCommonSimilarityMat - phenotypic similarity (mxm matrix)