Published October 23, 2021
| Version v1.0.0
Software
Open
Repository of the "Model-based estimation of transmissibility and reinfection of SARS-CoV-2 P.1 variant" code
Creators
- Renato Mendes Coutinho1
- Flávia Maria Darcie Marquitti2
- Leonardo Souto Ferreira3
- Marcelo Eduardo Borges4
- Rafael Lopes Paixão da Silva3
- Otavio Canton3
- Tatiana P. Portella5
- Silas Poloni3
- Caroline Franco3
- Mateusz M. Plucinski6
- Fernanda C. Lessa6
- Antônio Augusto Moura da Silva7
- Roberto Andre Kraenkel3
- Maria Amélia de Sousa Mascena Veras8
- Paulo Inácio Prado5
- 1. Universidade Federal do ABC, Santo André, SP, Brazil
- 2. Universidade Estadual de Campinas, Campinas, SP, Brazil
- 3. Universidade Estadual Paulista, São Paulo, SP, Brazil
- 4. Vigilância Epidemiológica, Secretaria de Saúde de Florianópolis, Florianópolis, SC, Brazil
- 5. Universidade de São Paulo, São Paulo, SP, Brazil
- 6. Centers for Disease Control and Prevention, Atlanta, USA
- 7. Universidade Federal do Maranhão, São Luís, MA, Brazil
- 8. Faculdade de Ciências Médicas da Santa Casa de São Paulo – São Paulo, SP, Brazil
Description
README
This repository provides the script to reproduce the fitting analysis and figures from Coutinho et al. 2021
Notes:
- This code runs best on R version 4.0.3 or above.
- The code is also optimized for [linux].
- When you first run the code from
Run_analysis.R
, R will install all required packages. - Running
all.params.exploration()
andfit_minima()
takes a large number of hours to complete. For convenience, we also provide the tables resulting from these function as .csv files.
Run the file Run_analysis.R
to reproduce the paper`s main analysis and sensitivity analysis.
The following values correspond to the parameters presented in Table 1:
- REL.BETA.RATE2: Relative transmission rate for the new variant
- PROB.REINFEC.V2: Relative force of reinfection of P.1
- prevalence: Prevalence of previous infection (2020-11-01) (%)
- INIT.V2.FRAC: Initial fraction of the new variant (2020-11-01)
- r: Intrinsic growth rate
- IHR.V2.PROP: odds ratio of P.1 parameters relative to wild variant
References:
Coutinho, R. M., Marquitti, F. M. D., Ferreira, L. S., Borges, M. E., da Silva, R. L. P., Canton, O., … & Prado, P. I. (2021). Model-based estimation of transmissibility and reinfection of SARS-CoV-2 P. 1 variant. medRxiv.
Files
covid19br/model-P1-variant-v1.0.0.zip
Files
(17.0 MB)
Name | Size | Download all |
---|---|---|
md5:333ff5cc78b5f3a53cb739631845b711
|
17.0 MB | Preview Download |
Additional details
Related works
- Is supplement to
- https://github.com/covid19br/model-P1-variant/tree/v1.0.0 (URL)