Published October 31, 2021
| Version v1
Journal article
Open
Performance of the 2017 and 2010 revised McDonald criteria in predicting MS diagnosis after a clinically isolated syndrome: a MAGNIMS Study
Creators
- Filippi, Massimo1
- Preziosa, Paolo1
- Meani, Alessandro1
- Dalla Costa, Gloria1
- Mesaros, Sarlota2
- Drulovic, Jelena2
- Ivanovic, Jovana2
- Rovira, Alex3
- Tintorè, Mar3
- Montalban, Xavier3
- Ciccarelli, Olga4
- Brownlee, Wallace4
- Miszkiel, Katherine4
- Enzinger, Christian5
- Khalil, Michael5
- Barkhof, Frederik6
- Strijbis, Eva MM6
- Frederiksen, Jette L7
- Cramer, Stig7
- Fainardi, Enrico8
- Amato, Maria Pia8
- Gasperini, Claudio9
- Ruggieri, Serena9
- Martinelli, Vittorio1
- Comi, Giancarlo10
- Rocca, Maria A.1
- 1. IRCCS San Raffaele Scientific Institute, Milan, Italy
- 2. University of Belgrade, Belgrade, Serbia
- 3. Hospital Universitari Vall d'Hebron, Barcelona, Spain
- 4. UCL Institute of Neurology, London, UK
- 5. Medical University of Graz, Graz, Austria
- 6. Amsterdam Neuroscience Amsterdam UMC, location VUmc, Amsterdam, The Netherlands
- 7. University of Copenhagen, Copenhagen, Denmark
- 8. University of Florence, Florence, Italy
- 9. San Camillo Forlanini Hospital, Rome, Italy
- 10. Vita-Salute San Raffaele University, Milan, Italy
Description
Primary research question: in patients with a typical CIS suggestive of MS, do the 2017 revision to the McDonald criteria outperform the 2010 McDonald criteria for the diagnosis of MS?
This study provides Class II evidence that the 2017 McDonald Criteria more accurately distinguish CDMS in patients early after a CIS when compared to the 2010 McDonald criteria.
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