ASSOCIATION OF THE ABO BLOOD GROUPS WITH DIAGNOSED CASES OF ISCHAEMIC HEART DISEASE

Objective: The main purpose of this study was to observe the association of the ABO Blood groups with diagnosed cases of Ischaemic Heart Disease with a more vigorous attempt to find coronary artery risk factor in predisposed blood groups and to evaluate the patients for coronary artery disease in predisposed blood group who are presenting with chest pain with normal E.C.G specially with predisposing coronary artery disease risk factors and/ or positive family history. Material & Methods: Study Design: Simple descriptive study. Study Setting: This study was conducted in the department of Cardiology Liaquat University Hospital at Hyderabad. Sample Size: Two Hundred One Patients. Duration of Study: Six Months, from September 2009 to February 2010. Sample Technique: Convenience. Results & Conclusion: The results obtained show that in 201 patients included in this study, the prevalence of IHD in blood group A is higher than in all other ABO groups. This study was conducted to assess the association of ABO blood group with IHD. It is found that blood group A+ is more associated with Ischaemic Heart Disease in our setup. This finding is also supported by the studies conducted in other parts of the world. This study also found that Dyslipidaemia is more common in blood group A+ individuals as compared to Hypertension and Diabetes Mellitus. The findings of our study indicate additional screening in the patients of predisposed blood group for IHD and its risk factors and can help the public and patients. The observations of the study also suggests for further research regarding molecular and genetic basis of association in IHD and ABO blood groups, especially in blood group A+. Key words: Association of ABO Blood Groups, Diagnosed Cases, Ischaemic Heart Disease