D3.2 - Project Manual – CoBraD RWD, Updated MES-CoBraD Protocols and Quality and Quantity (Q&Q) Evaluation – v2

The current Project Manual (PM) aims to be a continuously updated reference on (a) metrics that are
assessed in people with CoBraD belonging to the above categories of RWD, (b) their systematic and
standardised quality requirements, and (c) the agreed upon multisource RWD acquisition protocols. The
PM reflects the foundation of the project’s scientific roadmap by contributing directly to work packages
relating to pilot data collection, CoBraD phenotyping and outcome assessment, within the framework of
the integrated clinical-research MES-CoBraD Platform. On this basis, it is a reference for users involved
in the MES-CoBraD Project.